There are currently 5 FDA-approved HPV assays – each has a different number of results, based on the different hr-HPV genotypes detected and whether these genotypes are reported as a grouped result or as an individual result.

Pooled results Individual results No genotyping 3 results in primary run HC2 cobas ® Aptima ® Cervista™ HPV HR BD Onclarity™ HPV Assay 35 39 51 56 59 68 31 33 52 58 45 18 16 35 39 51 56 59 66 68 31 33 52 58 45 18 16 1 result in primary run* 35 39 51 56 59 66 68 31 33 52 58 45 18 16 1 result in primary run* 35 39 51 56 59 66 68 31 33 52 58 45 18 16 9 results in primary run 35 39 68 56 59 66 58 33 18 31 51 52 45 16

*2nd assay & processing run required for 3 results
Adapted from Salazar K et al. J Am Soc Cytopath. 2019;8:284–92.